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Reduced selenium levels have also been associated with the consumption of eggs, white rice, alcohol, and coffee, in addition to smoking

Preclinical studies confirm that targeting HSP90 effectively ameliorates depressive-like behaviors: quercetin inhibits HSP90 to suppress NLRP3 inflammasome activation and levels of cytokines (IL-6, IL-1, and TNF-), alleviating hippocampal neuroinflammation [30]